Polyphenol extract from evening primrose pomace alleviates experimental colitis after intracolonic and oral administration in mice
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منابع مشابه
Influence of polyphenol extract from evening primrose (Oenothera paradoxa) seeds on human prostate and breast cancer cell lines.
There is growing interest in plant polyphenols which exhibit pleiotropic biological activities, including anti-inflammatory, antioxidant, and anticancer effects. The objective of our study was to evaluate the influence of an evening primrose extract (EPE) from defatted seeds on viability and invasiveness of three human cell lines: PNT1A (normal prostate cells), DU145 (prostate cancer cells) and...
متن کاملEvening Primrose Oil/CD
In a double-blind trial patients with atopic eczema received either oral evening primrose oil (EPO) (n = 14) or placebo (n = 11) for 12 weeks. In the EPO group a statistically significant improvement was observed in the overall severity and grade of inflammation and in the percentage of the body surface involved by eczema as well as in dryness and itch. Patients in the placebo group showed a si...
متن کاملAnti-Helicobacter pylori activities of FEMY-R7 composed of fucoidan and evening primrose extract in mice and humans
Helicobacter pylori-eliminating effects of FEMY-R7, composed of fucoidan and evening primrose extract, were investigated in mice and humans. Male C57BL/6 mice were infected with the bacteria by intragastric inoculation (1×10(9) CFU/mouse) 3 times at 2-day intervals, and simultaneously, orally treated twice a day with 10 or 100 mg/kg FEMY-R7 for 2 weeks. In Campylobcter-like organism-detection t...
متن کاملReactive oxygen species-independent G1 arrest induced by evening primrose extract in Ehrlich ascites tumor cells.
We previously demonstrated that evening primrose extract (EPE) induced apoptosis in Ehrlich ascites tumor cells (EATC), and this effect was specific on tumor cells. Furthermore, our results demonstrated that EPE exposure elicited a rapid increase in the activity of superoxide dismutase and intracellular peroxides levels. These changes caused translocation of Bax to mitochondria and a subsequent...
متن کاملCaspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells.
We previously demonstrated that evening primrose extract (EPE) induced apoptosis in Ehrlich ascites tumor cells, while mouse embryo fibroblast cells (NIH3T3) used as a normal cell model, showed no effect of cell viability by treatment of EPE. Furthermore, our results demonstrated the rapid increase in intracellular peroxides levels, loss of mitochondrial membrane potential and the release of cy...
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ژورنال
عنوان ژورنال: Naunyn-Schmiedeberg's Archives of Pharmacology
سال: 2014
ISSN: 0028-1298,1432-1912
DOI: 10.1007/s00210-014-1025-x